Two affiliates of the U.S. hedge fund SAC Capital Advisors agreed to pay more than 614 million dollars to settle separate insider trading charges, the U. S. Securities and Exchange Commission (SEC) said on Friday.

The SEC charged SAC's CR Intrinsic division in November 2012, alleging that one of the firm's portfolio managers Mathew Martoma illegally obtained confidential details about the clinical trial from a doctor before the final results went public and the firm made profit from trading on the nonpublic information.

CR Intrinsic agreed to pay over 600 million dollars to settle the charge, the largest ever settlement in an insider trading case, the SEC said.

"The historic monetary sanctions against CR Intrinsic and its affiliates are sharp warning that the SEC will hold hedge fund advisory firms and their funds accountable when employees break the law to benefit the firm," said George Canellos, Acting Director of the SEC's Division of Enforcement.

Sigma Capital Management, another SAC unit, on Friday also agreed to pay nearly 14 million dollars to settle allegations that the firm engaged in insider trading ahead of the quarterly earnings of Dell and Nvidia Corporation.

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