BEIJING, Nov. 20 (Xinhua) -- The following are the updates on the global fight against the COVID-19 pandemic.

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RIO DE JANEIRO -- The Brazilian government said Thursday that the country may be experiencing a possible second wave of COVID-19, as cases and deaths began to rise in recent days.

Economy Minister Paulo Guedes said that if a second wave of COVID-19 is confirmed in Brazil, the government will tackle the problem as it did for the first time, but with more experience.

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LOS ANGELES -- California governor Gavin Newsom announced on Thursday a mandatory overnight stay-at-home order limiting non-essential work, movement and gatherings in the most populous U.S. state to slow down the spread of COVID-19.

The order requires generally that non-essential work, movement and gatherings stop between 10 p.m. and 5 a.m. local time in counties in the purple tier, where COVID-19 transmission rates are highest. The order will take effect on Nov. 21 and remain in effect until Dec. 21, according to the office of the governor.

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LONDON -- The antiviral drug remdesivir should not be used to treat COVID-19 patients no matter how ill they are as there is no evidence it works, the World Health Organization (WHO) said on Friday.

"The ... panel found a lack of evidence that remdesivir improved outcomes that matter to patients such as reduced mortality, need for mechanical ventilation, time to clinical improvement, and others," said the WHO's Guideline Development Group (GDG) panel.

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BEIJING -- The Chinese mainland on Thursday reported no new locally transmitted COVID-19 cases, the National Health Commission said Friday.

A total of 17 imported COVID-19 cases were reported across the mainland Thursday. Of the new imported cases, six were reported in Fujian, four in Shanghai, three in Shaanxi, two in Guangdong, and one each in Beijing and Sichuan, the commission said in its daily report. Enditem

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