US scientists blend AI, 3D tissue imaging to identify aggressive prostate cancer

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Researchers at the Case Western Reserve University and the University of Washington are expected to gain valuable new insights into highly aggressive prostate cancer by combining Artificial Intelligence (AI)-powered diagnostic imaging with three-dimensional (3D) tissue imaging, according to a release.

This new AI-3D collaboration will provide a never-before-seen, expanded view and understanding of prostate cancer cells, made possible by a new approach called "light sheet microscopy," said the researchers.

Prostate cancer is the most common non-skin cancer in the United States. One in eight men nationally will be diagnosed with prostate cancer in his lifetime, and one in 40 will die from the disease, according to the Prostate Cancer Foundation.

"This is an unprecedented meshing of the two most powerful technologies in this area," said Anant Madabhushi, director of the Center for Computational Imaging and Personalized Diagnostics at the Case Western Reserve University.

"We'll take the AI we've developed and, for the first time, be able to apply it to 3D tissue-imaging that the University of Washington excels in-and gain fine, granular detail," he said.

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