Combined therapy for hypertension and dyslipidemia (high
cholesterol level) can reduce cardiovascular disease risk by over
half, said a study result made public Thursday by the University of
The study, headed by the university's faculty of medicine, was
the world's first large-scale clinical trial to assess the
real-world clinical effectiveness and safety of combined therapy
for the management of hypertension and dyslipidemia. It involved a
total of 1,649 patients in 27 countries and regions.
Patients involved in the study took a single-pill combination of
amlodipine besylate and atovastatin calcium to treat both
hypertension and dyslipidemia over 14 weeks.
Improvements in blood pressure and low density lipoprotein
cholesterol were observed as early as four weeks into the trial. By
the end of the trial period, a mean percentage reduction in
cardiovascular risk of 58 percent was observed in Hong Kong
Results of the study have been released in October 2006 at the
21st Scientific Meeting of the International Society of
Hypertension in Japan.
(Xinhua News Agency January 26, 2007)