Manchester United manager Alex Ferguson will call on a rested Cristiano Ronaldo and Wayne Rooney to fire his side into the Champions League quarter-finals at the expense of Olympique Lyon on Tuesday.

The duo came on as late second-half substitutes as United brushed Fulham aside 3-0 on Saturday to maintain their pursuit of Premier League leaders Arsenal.

The tie with French champions Lyon is evenly poised, albeit with United having an away goal in the bank after a late Carlos Tevez strike secured United a 1-1 draw in Lyon last week.

United have an impressive Champions League home record and conceded just one goal in three group games at Old Trafford this season. They have also not lost at home to a French side in European competition.

"We've got to win against Lyon - it's a massive game for the club. All the players realise that," Ferguson told the club's Web site.

"The pleasing thing for me was I was able to use my squad with Tuesday's game with Lyon in mind. It was vital for us to rest Ronaldo and Rooney."

Winger Ryan Giggs was rested for Saturday's clash against Fulham after picking up a calf strain while Serbian defender Nemanja Vidic was absent through injury.